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(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol has been developed by Specpharms as a key intermediate for NK-1 receptor antagonist
2016-01-19         
(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol is a key intermediate for NK-1 receptor antagonist used to treat chemotherapy-induced nausea and vomiting (CINV). Until now, three drugs, viz. Aprepitiant, Fosaprepitant Dimeglumine and Rolapitant hydrochloride hydrate have been approved as NK-1 receptor antagonist to treat CINV.
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